Antibiotics are what we think of significant infection cases because of their effectiveness to control bacteria proliferation and disease control. But a control in the antibiotic application is the need of the hour as the improper use of antibiotics are leading to antibiotic resistance in bacteria Antimicrobial resistance is considered as one of the major health threats globally but along with that antibacterial resistance is one the rise and tops the chart for serious health threat.

Department of Biotechnology has revealed a report saying that India is reported to have the highest rate of antibiotic-resistant bacteria that cause infection in community and healthcare facility. This report known as Scoping Report was jointly prepared by the DBT and Research Councils United Kingdom (RCUK) by the Centre for Disease Dynamics, Economics & Policy, India (CDDEP).

Carbapenems group of antibiotic are the last generation antibiotics known to cure the severe bacterial infection, but several gram-negative bacteria have grown resistance to them. To be specific, the highest carbapenems resistance was observed in A. baumannii (67.3%; 70.9%) which is usually acquired through hospital generated infections. This was followed by K. pneumoniae (56.6%; 56.6%) leading to pneumonia, blood infections, etc., P. aeruginosa (46.8%; 41.8%) causing urinary tract infection, and E. coli (11.5%; 16.2%) that can lead to food poisoning. Doctors have a tough time treating patients with drugs which have been resistant to bacteria.

But why there is arise in the antibiotic resistance by bacteria? A study by Dr. Yatin Mehta, chairman, Institute of Critical Care & Anesthesiology, Medanta reveals that patients coming from small town usually take 1st or 2nd line antibiotic and would have already grown bacteria resistance because of the improper and uncared use of those drugs.

So how do we stop this AMR situation from further degrading is the answer you must be seeking? The significant criteria involves improving awareness and understanding of AMR through effective communication, education, and training; strengthening knowledge and evidence through surveillance; reducing the incidence of infection through effective infection prevention and control; optimizing the use of antimicrobial agents in health, animals and food; promoting investments for AMR activities, research and innovations; and strengthening India’s leadership on AMR.

Image Source: jamanetwork.com